Inflammatory Biomarkers and Cardiovascular Ageing
Cardiovascular ageing is shaped by complex interactions between immune activity, metabolic risk, and life-course exposures. My research investigates how inflammatory and metabolic biomarkers influence the development of cardiovascular disease, chronic pain, and multimorbidity across the lifespan.
Using large longitudinal cohort datasets, I examine how biological markers such as CRP, IL-6, and composite inflammatory indices relate to disease trajectories in aging populations. This work integrates epidemiology, biostatistics, and translational medicine to better understand how immune dysregulation contributes to age-related cardiovascular risk, and how systemic inflammatory processes may link cardiovascular and neurocognitive ageing.
Research Focus
- Inflammatory biomarkers and cardiometabolic risk
- Biomarker-based phenotyping of aging populations
- Immune dysregulation and chronic disease trajectories
- Integration of molecular biomarkers with longitudinal cohort data
Data and Analytical Approach
This research relies on large longitudinal population cohorts and advanced statistical modelling to examine biomarker–disease associations across the lifespan. By integrating biological markers with clinical and socio-demographic data, the work aims to identify pathways linking immune activation, cardiometabolic risk, multimorbidity, and broader ageing trajectories, including emerging links between cardiovascular and neurocognitive health.